Fiatfon


PRESCRIPTION

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Famotidine, a competitive histamine H -receptor antagonist, is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and 2 pathological hypersecretory conditions. Famotidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Famotidine include an increase in gastric bacterial flora, such as nitrate-reducing organisms.

Manual

Fiatfon 20 mg. Each film-coated tablet contains:

Famotidine BP 20 mg.

Approved colours used in coating

Fiatfon 40 mg: Each film-coated tablet contains:

Famotidine BP 40 mg.

Approved colours used in coating

Fiatfon should be used with the following indications:

  • Peptic ulcer and 12 duodenal ulcer;
  • Gastric hyperacidity, heartburn (associated with hyperacidity);
  • Symptomatic and stress ulcers of the gastrointestinal tract;
  • Erosive reflux esophagitis;
  • NSAID-gastropathy;
  • Zollinger-Ellison syndrome;
  • Systemic mastocytosis;
  • Multiple endocrine adenomatosis;
  • Prevention of recurrence bleeding in the postoperative period;
  • Prophylaxis of aspiration of gastric juice in patients undergoing surgery under general anesthesia (Mendelson’s syndrome);
  • Aspiration pneumonia (prevention);
  • Dyspepsia with epigastric or retrosternal pain, appearing at night or related to food intake.

Acute gastric ulcer and 12 duodenal ulcer – 40 mg once a day at bedtime or 20 mg two times a day. If necessary, the daily dose can be increased to 80-160 mg. Duration of treatment – 4–8 weeks.

Prevention of relapse of peptic ulcer- 20 mg once a day at bedtime.

Zollinger-Ellison syndrome – an initial dose of 20 – 40 mg 4 times a day, if necessary, the daily dose can be increased to 240-480 mg. Treatment continued so long as is necessary (severe symptoms – up to 160 mg every 6 hours).

Reflux esophagitis initial dose – 20 mg 2 times a day for up to6 weeks (if needed – 20–40 mg 2 times a day for up to 12 weeks).

Prevent aspiration of gastric contents – 40 mg before surgery or in the morning of surgery.

Patients with a creatinine clearance of less than 10 ml/min – 20 mg at bedtime.

Interval between doses may be increased to 36–48 hours.