Amokvart

Amokvart 125 mg: Each 5 ml of reconstituted suspension contains:

Amoxicillin Trihydrate BP eq. to Amoxicillin 125 mg;
Excipients q.s.

Amokvart 250 mg: Each 5 ml of reconstituted suspension contains:

Amoxicillin Trihydrate BP eq. to Amoxicillin 250 mg;
Excipients q.s

Amoxicillin is a broad-spectrum aminopenicillin and is indicated in the treatment of bacterial infections such as:

• actinomycosis;
• biliary-tract infections;
• bone and joint infections;
• acute exacerbations of chronic bronchitis;
• gastroenteritis (including Escherichia coli enteritis and Salmonella enteritis, but not shigellosis);
• gonorrhea;
• mouth infections, sinusitis, otitis media, pneumonia (except where Mycoplasma suspected);
• typhoid and paratyphoid fever;
• urinary-tract infections;
• bacterial meningitis and the prophylaxis of endocarditis;
• Lyme disease.

Dosage and directions for use: 

Standard Adult Dosage: 5ml of 250mg/5ml suspension three times daily, increasing to 10ml of 250mg/5ml suspension three times daily for more severe infections. High dose and short course therapies, requiring doses of up to 6 g, daily, a more appropriate dosage form is recommended.

Children weighing more than 40 kg should be given the usual adult dosage.
Children weighing < 40 kg
The daily dosage for children is 40 – 90 mg/kg/day in two to three divided doses* (not exceeding 3 g/day) depending on the indication, severity of the disease and the susceptibility of the pathogen. *PK/PD data indicate that dosing three times daily is associated with enhanced efficacy, thus twice daily dosing is only recommended when the dose is in the upper range.

Special dosage recommendation:

Tonsillitis: 50 mg/kg/day in two divided doses.
Acute otitis media: In areas with high prevalence of pneumococci with reduced susceptibility to penicillins, dosage regimens should be guided by national/local recommendations.
Prophylaxis for endocarditis: 50 mg amoxicillin/kg body weight, given as a single dose one hour preceding the surgical procedure.

Dosage and directions for use:

Adult Dosage (including elderly patients).
Standard Adult Dosage: 5ml of 250mg/5ml suspension three times daily, increasing to 10ml of 250mg/5ml suspension three times daily for more severe infections. High dose and short course therapies, requiring doses of up to 6 g, daily, a more appropriate dosage form is recommended.

Children weighing more than 40 kg should be given the usual adult dosage.
Children weighing < 40 kg
The daily dosage for children is 40 – 90 mg/kg/day in two to three divided doses* (not exceeding 3 g/day) depending on the indication, severity of the disease and the susceptibility of the pathogen. *PK/PD data indicate that dosing three times daily is associated with enhanced efficacy, thus twice daily dosing is only recommended when the dose is in the upper range.

Special dosage recommendation:

Tonsillitis: 50 mg/kg/day in two divided do
Acute otitis media: In areas with high prevalence of pneumococci with reduced susceptibility to penicillins, dosage regimens should be guided by national/local recomations.
Prophylaxis for endocarditis: 50 mg amoxicillin/kg body weight, given as a single dose one hour preceding the surgical procedure.